Anti-inflammatory Therapy in Managing Reversible Airway Diseases
Inflammation plays a central role in reversible airway diseases, and anti-inflammatory therapy is key to long-term symptom control. Inhaled corticosteroids are the most commonly prescribed agents, targeting airway swelling and reducing hypersensitivity to triggers.
Daily use of inhaled corticosteroids decreases the frequency and severity of flare-ups. They act locally within the lungs, minimizing systemic side effects while maintaining efficacy. Patients with persistent symptoms may also benefit from combination therapy with long-acting bronchodilators for enhanced airflow and reduced inflammation.
Systemic corticosteroids are reserved for severe exacerbations. Although highly effective, prolonged use is associated with side effects such as weight gain, mood changes, and increased infection risk. Clinicians carefully weigh these risks when prescribing short-term courses.
Other anti-inflammatory options, such as leukotriene receptor antagonists, help block pathways responsible for airway constriction. They are particularly beneficial for patients with allergen-driven symptoms or exercise-induced episodes.
Effective anti-inflammatory therapy requires patient adherence, regular monitoring, and education. Proper use, awareness of side effects, and follow-up evaluations ensure optimal outcomes and help prevent irreversible airway remodeling.